課程資訊
課程名稱
專題討論
Seminar 
開課學期
103-2 
授課對象
生化科技研究所  
授課教師
楊啟伸 
課號
BST7000 
課程識別碼
B22 M0020 
班次
04 
學分
全/半年
半年 
必/選修
必修 
上課時間
星期一7,8(14:20~16:20) 
上課地點
農化一第六 
備註
必修4學期與黃慶璨、張麗冠、陳進庭、林晉玄合開
限碩士班以上
總人數上限:42人 
Ceiba 課程網頁
http://ceiba.ntu.edu.tw/1032BST7000_04 
課程簡介影片
 
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課程概述

專題討論 

課程目標
待補 
課程要求
待補 
預期每週課後學習時數
 
Office Hours
 
指定閱讀
待補 
參考書目
待補 
評量方式
(僅供參考)
   
課程進度
週次
日期
單元主題
第2週
3/02  【課程說明及準備】:上課內容說明, 同學時程安排和確認, 上學期課程之回顧和討論 
第3週
3/09  【張麗冠老師分享學術演講及研究心得】 
第4週
3/16  <mark>【博士班同學】</mark>
【黃柄翰】<br>Genome editing. The new frontier of genome engineering with CRISPR-Cas9.<br><b><i>Science 346:1258096 (2014).</b></i> 
第5週
3/23  【沈縵】<br>Liposomes as nanomedical devices <br /> <b><i>International Journal of Nanomedicine 10:975–999 (2015)</b></i>. 
第6週
3/30  -- 順延至 4/13 上課 --  
第7週
4/06  -- 不上課 --
(清明節補休) 
第8週
4/13  【黃睦晴】<br /> Functions and therapeutic roles of exosomes in cancer <br /><b><i> Frontiers in Oncology 4(127): 1-8 (2014)</b></i>.<br /> <mark>【碩士班一年級同學】</mark>
【吳智宇】<br />Bacterial Lipopolysaccharide Binding Enhances Virion Stability and Promotes Environmental Fitness of an Enteric Virus<br /><b><i>Cell Host Microbe. 15(1):36-46 (2014)</b></i>.
【黃湘燕】<br />Wool-waste valorization: production of protein hydrolysate with high antioxidative potential by fermentation with a new keratinolytic bacterium, <i>Bacillus pumilus A1 </i><br /> <i><b>Journal of Applied Microbiology 115(2):424-433 (2013)</i></b>. 
第9週
4/20  【王開立】<br> A new antibiotic kills pathogens without detectable resistance <br /><b><i>Nature 517(7535):455-459 (2015).</b></i><br />【翁筠婷】<br />HSV-1 Remodels Host Telomeres to Facilitate Viral Replication <br /><b><i>Cell Reports 9(6):2263-2278 (2014)</b></i>. 
第10週
4/27  【黃元祈】<br /> Sensitizing Protective Tumor Microenvironments to Antibody-Mediated Therapy. <br /><b><i>Cell. 156(3):590-602. doi: 10.1016/j.cell.2013.12.041.</b></i>.
【殷群】<br />HCMV pUL135 Remodels the Actin Cytoskeleton to Impair Immune Recognition of Infected Cells<br /><b>Cell Host & Microbe 16, 201–214, August 13, 2014<i></b></i>.
 
第11週
5/04  【黃儀真】<br>CLIC4 regulates TGF-β dependent myofibroblast differentiation to produce a cancer stroma<br /> <b><i> Oncogene 33 842-850 (2014) </b></i>.
【陳則堯】<br /> EBV Noncoding RNA Binds Nascent RNA to Drive Host PAX5 to Viral DNA <br /><b><i>Cell 160(4):607–618 (2015)</b></i>. 
第12週
5/11  【簡琇羽】<br />Listeria phospholipases subvert host autophagic defenses by stalling pre-autophagosomal structures. <br /><b><i>The EMBO Journal (2013) 32, 3066–3078 </b></i>.
【林俞均】<br /> Staphylococcus epidermidis in the human skin microbiome mediates fermentation to inhibit the growth of Propionibacterium acnes : implications of probiotics in acne vulgaris <br /><b><i>Applied Microbiology and Biotechnology 98:411-424 (2014)</b></i>. 
第13週
5/18  【蔡曉涵】<br />USP30 and parkin homeostatically regulate atypical ubiquitin chains on mitochondria.<br/><b><i> Nature Cell Biology 17:160-169 (2015) </b></i>.
【侯健睿】<br />A self&#173;produced trigger for biofilm disassembly that targets exopolysaccharide.<br /><b><i>Cell 149(3):684&#173;692 (2012)</b></i>. 
第14週
5/25  <mark>【碩士班二年級畢業論文進度報告】</mark>
【張雯涵】<br />白色念珠球菌 Hog1 蛋白質內的兩個磷酸化點對於 White-Opaque 型態轉換、交配能力及費洛蒙誘導細胞附著之重要性 <br />Two Conserved Phosphorylation Sites of The Candida albicans Hog1 Protein Are Important for White-Opaque Switching, Mating Response and Pheromone-Stimulated Cell Adhesion 
第15週
6/01  【陳筱儒】<br /> 鹽方扁平古菌中氯視紫紅質光動離子泵功能的探討 <br /> Investigation on light-driven ion trans-location capability of halorhodopsin from <i>Haloquadratum walsbyi</i> 
第16週
6/08  【楊尉屏】<br /> 以紫杉醇和阿黴素引發之hTERT表現量下降探討hTERT的調控機制 <br /> Investigating the molecular mechanisms involved in hTERT down-regulation induced by Taxol and Doxorubicin <br />【許巧青】<br />The correlation between fluorescence intensity and target protein in 2A-mediated co-expression of different EGFPs and GMI-L6C 
第17週
6/15  【陳佩君】<br />從台灣分離之嗜鹽古細菌光趨性分析與其感受型視紫紅質之特性 <br />Characterization on sensory rhodopsins from a native halobacterium isolated from Taiwan.<br /> 【林佳葳】<br />選殖金針菇不同單元萎銹靈抗性基因及探討金針菇同源性篩選系統之穩定性<br /> Cloning cytochrome b560 subunit of succinate dehydrogenase complex (Complex II) and comparison of different carboxin resistance gene for homologous selectable system in <i>Flammulina velutipes</i>